Technology Overview

Not all people respond to medications in the same way. Traditional dosing solutions use population-based pharmacokinetic models. Our precision dosing solution uses real-time feedback to create a patient-specific model that informs future dosing. It automatically pulls patient-specific data from the electronic healthcare record and generates model-informed recommendations via an intuitive graphical interface, providing all the actionable information directly to the physician and clinical teams in a comprehensible format from connected devices. Clinicians can track the amount of drug and biomarkers in the body as a dynamic “molecular state,” in vivo, and in real time.

Applications

Recommends dosing for a variety of conditions that require tightly controlled treatment regimens. Tested in opioids for pain, and dosing for sickle cell disease, inflammatory bowel disease, and allogeneic hematopoietic cell transplantation for non-malignant disorders.

Advantages

• Designed by clinicians for clinicians (potential for faster adoption and higher utilization).
  
• Assists clinical workflow by reducing time spent interpreting lab results and ordering.

Market Overview

Inadequate pain relief and serious side effects from perioperative opioids occur frequently in up to 50% of patients. ~70K-100K Americans have sickle cell disease. ~3 million U.S. adults have received a diagnosis of inflammatory bowel disease.

Investigator Overview

Alexander Vinks, PharmaD, Ph.D. and Tracy Glauser, M.D.