Innovation Ventures

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  • Behavioral Medicine & Nephrology

    Digitally-Enabled Adherence Platform (DEAP)

    A software platform to monitor and improve patients' adherence to medications and treatments.

  • Gastroenterology

    Biomarker Response Signatures of Children Receiving Infliximab for Crohn’s Disease

    Plasma Proteomic Response Signature of Children Receiving Infliximab for Crohn’s Disease

  • Drug Delivery

    Morcellator for use with Feeding Tubes

    A prototype of a self-contained morcellator for preparing medication for feeding tube delivery

  • Dermatology

    Thrombin Inhibitor as Novel Oral Treatment for Atopic Dermatitis

    A newly established link between the mechanistic role of thrombin and fibrinogen and their contribution to AD provides a novel mechanism for oral treatment.

  • Allergy

    Activation of Aryl Hydrocarbon Receptor (AHR) as a therapeutic for Eosinophilic Esophagitis (EoE).

    Recent studies have linked the importance of AHR as a regulator of EoE pathogenesis and the potential of AHR activation by small molecules as EoE therapy.

  • Gastroenterology

    Elevated Oncostatin M Predicts Non-response to Anti-TNF Therapy

    Oncostatin M biomarkers are associated with non-response to Infliximab therapy

  • Genetic Diseases

    Novel Treatment to Ensure Efficacious Dosage for Multiple, Rare Genetic Diseases

    Optimal dosing regimen for treating seizures and self-aggressive behavior

  • Oncology

    Small Molecule VAV3 Inhibitor as Novel Cancer Therapeutic

    Our proprietary inhibitor binds to VAV3 thereby inhibiting the activation of RAC downstream of several oncogenes.

  • Immunology

    Small molecule perforin inhibitors to enhance vaccine efficacy

    Perforin inhibition during vaccination can improve vaccine success against a variety of infections and diseases for which sufficiently efficacious immune response has proven difficult

  • Gene and Cell therapy

    Stem Cell & Organoid Medicine

    Organoids provide an unprecedented opportunity to study human organ development and physiology, and investigate the cause of disease.

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Cincinnati Children’s Innovation Ventures

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