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"Oncology, Inflammation"
Pharmacologic and genetic inhibition of UBE2N suppresses the function and viability of MDS/AML cells lines and patient samples. A commercially available and a novel compound has been identified.
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Dermatology
Rapid reliable method for collection of keratinocyte RNA, DNA, microbiome, proteins, lipids, and metabolites.
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Surgery
Spheric endo-luminal traction device helps improve surgical outcomes for individuals with long-gap esophageal atresia
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Neurology
Dantrolene is an antagonist of ryanodine receptors (Ryrs) and blocks Ryr-mediated endoplasmic reticulum calcium release. It is an FDA-approved drug.
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Drug Delivery & Formulation
A validated algorithm to calculate when the next dose of an inhibitor of complement-mediated (C5) activity is required.
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Allergy
Deficiency of SPINK7 is a novel regulator of pro-inflammatory cytokine production in eosinophilic esophagitis.
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Health IT & Biomedical Informatics
Structured and natural language processing techniques used to match patients to clinical trials from EHR data.
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Data mining and analysis
Novel Approach to datamining and synthesizing Information from very large drug, disease, and adverse effects databases
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Allergy
Pharmacological targeting of NTRK1 using small molecule inhibitors may reduce allergic inflammation.
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Nephrology
Biomarker panel for distinguishing idiopathic steroid resistant vs. steroid sensitive nephrotic syndrome.